Concepedia

TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes

Anna Yarilina, Kyung‐Hyun Park‐Min, Taras T. Antoniv, Xiaoyu Hu, Lionel B. Ivashkiv

Nature Immunology · 2008 · 433 citations · 39 references

DOI

Concepts

References

39

IKKε and TBK1 are essential components of the IRF3 signaling pathway

Katherine A. Fitzgerald, Sarah M. McWhirter, Daniel C. Rowe et al. · Nature Immunology · 2003 · 2.7K citations

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IRF-7 is the master regulator of type-I interferon-dependent immune responses

Kenya Honda, Hideyuki Yanai, Hideo Negishi et al. · Nature · 2005 · 2.2K citations

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Decoding the Patterns of Self and Nonself by the Innate Immune System

Ruslan Medzhitov, Charles A. Janeway · Science · 2002 · 2.2K citations

, , +17

Triggering the Interferon Antiviral Response Through an IKK-Related Pathway

Sonia Sharma, Benjamin R. tenOever, Nathalie Grandvaux et al. · Science · 2003 · 1.7K citations

, , +17

Differential viral induction of distinct interferon‐α genes by positive feedback through interferon regulatory factor‐7

Isabelle Marié · The EMBO Journal · 1998 · 1K citations · Full text

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