Clinical and EEG manifestations of an unusual aphasic syndrome in children

Abstract

Three cases of acquired aphasia in childhood associated with marked spike-wave discharges with temporal lobe predominance are described. The degree of aphasia paralleled the EEG abnormalities; spike-wave discharges were almost continuous when the language disorder was at its peak. Improvement in the language disorder coincided with reduction in the number of paroxysmal discharges or with a change to focal origin. The aphasia appears to be the result of an underlying pathophysiology causing the abnormal EEG activity, and not the result of a gross structural lesion.