Rapid screening and sensitive detection of NPM1 (nucleophosmin) exon 12 mutations in acute myeloid leukaemia

Cytoplasmic Nucleophosmin in Acute Myelogenous Leukemia with a Normal Karyotype

Brunangelo Falini, Cristina Mecucci, Enrico Tiacci et al. · New England Journal of Medicine · 2005 · 1.9K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +14

LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition

Alexei A. Koshkin, Sanjay K. Singh, Poul Nielsen et al. · Tetrahedron · 1998 · 1K citations

Pharmacy, Biochemistry, Molecular Biology +16

Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations

Konstanze Döhner, Richard F. Schlenk, Marianne Habdank et al. · Blood · 2005 · 845 citations · Full text

Life Sciences, Genetics, Oncology +11

Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype

Susanne Schnittger, Claudia Schoch, Wolfgang Kern et al. · Blood · 2005 · 704 citations · Full text

Life Sciences, Molecular Genetics, Oncology +14

Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance

Roel G.W. Verhaak, Chantal S. Goudswaard, Wim van Putten et al. · Blood · 2005 · 617 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14