Increased Beta2-Adrenoceptors in Doxorubicin-Induced Cardiomyopathy in Rat

Abstract

This study highlights the β1/β2-AR imbalance in early Dox-CM and reveals the important role that β2-AR/Gi coupling could play in this pathology. Our results suggest that β2-AR could be an interesting target at early stage of Dox-CM.