Concepedia

Tumor Regression and Autoimmunity in Patients Treated With Cytotoxic T Lymphocyte–Associated Antigen 4 Blockade and Interleukin 2: A Phase I/II Study

Ajay V. Maker, Giao Q. Phan, Peter Attia, James Chih‐Hsin Yang, Richard M. Sherry, Suzanne L. Topalian, Udai S. Kammula, Richard E. Royal, Leah Haworth, Catherine Lévy,

Annals of Surgical Oncology · 2005 · 489 citations · 20 references

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20

Enhancement of Antitumor Immunity by CTLA-4 Blockade

Dana R. Leach, Matthew F. Krummel, James P. Allison · Science · 1996 · 3.9K citations

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Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4

Takeshi Takahashi, Tomoyuki Tagami, Sayuri Yamazaki et al. · The Journal of Experimental Medicine · 2000 · 2.2K citations · Full text

Cytotoxic T Lymphocyte–Associated Antigen 4 Plays an Essential Role in the Function of Cd25+Cd4+ Regulatory Cells That Control Intestinal Inflammation

Simon Read, Vivianne Malmström, Fiona Powrie · The Journal of Experimental Medicine · 2000 · 2.2K citations

A Cell Culture Model for T Lymphocyte Clonal Anergy

Ronald H. Schwartz · Science · 1990 · 1.9K citations

, , +13

CTLA-4 is a second receptor for the B cell activation antigen B7.

Peter S. Linsley, William Brady, M Urnes et al. · The Journal of Experimental Medicine · 1991 · 1.7K citations · Full text

, , +14