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The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-κB and c-Myc in pancreatic cancer cells

Tumor BiologyTranscriptional RegulationSignal TransductionSignaling PathwayPancreatic CancerCell RegulationMedicinePten ExpressionCancer Cell BiologyPancreatic Cancer CellsTumor SuppressorSystems BiologyCancer BiologyCell BiologyCell SignalingCancer ResearchMolecular Signaling