Concepedia

Pilot trial of intravenous infusion of a replication-selective adenovirus (ONYX-015) in combination with chemotherapy or IL-2 treatment in refractory cancer patients

John Nemunaitis, Charles Cunningham, A W Tong, Leonard Post, George J. Netto, A. S. Paulson, David Q. Rich, A Blackburn, Bruce E. Sands, B Gibson,

Cancer Gene Therapy · 2003 · 90 citations · 71 references

DOI

Concepts

References

71

Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment

Thomas J. Wickham, Patricia Mathias, David A. Cheresh et al. · Cell · 1993 · 2.2K citations

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An Adenovirus Mutant That Replicates Selectively in p53- Deficient Human Tumor Cells

James R. Bischoff, David H. Kirn, Angelica Williams et al. · Science · 1996 · 1.8K citations

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Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations.

Mary Ann Jordan, Robert Toso, Douglas Thrower et al. · Proceedings of the National Academy of Sciences · 1993 · 1.1K citations · Full text

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A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

Fadlo R. Khuri, John Nemunaitis, Ian Ganly et al. · Nature Medicine · 2000 · 1.1K citations

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Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses

Ya‐Wen Yang, Qunyang Li, Hildegund C.J. Ertl et al. · Journal of Virology · 1995 · 1K citations · Full text

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