REACH, non-testing approaches and the urgent need for a change in mind set

Application of the threshold of toxicological concern (TTC) to the safety evaluation of cosmetic ingredients

R. Kroes, A. G. Renwick, V.J. Feron et al. · Food and Chemical Toxicology · 2007 · 1.8K citations

Pharmacy, Toxicology, Food Toxicology +7

Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH)

Werner Lilienblum, W. Dekant, Heidi Foth et al. · Archives of Toxicology · 2008 · 313 citations

Pharmacy, Risk Management, Toxicology +16

The ECVAM International Validation Study on in Vitro Tests for Acute Skin Irritation: Report on the Validity of the EPISKIN and EpiDerm Assays and on the Skin Integrity Function Test

Horst Spielmann, Sebastian Hoffmann, Manfred Liebsch et al. · Alternatives to Laboratory Animals · 2007 · 223 citations

Pharmacy, Dermatology, Toxicology +11

Alternative Approaches Can Reduce the Use of Test Animals under REACH.

Van Der Jagt Katinka, Munn Sharon j., Jens Tørsløv et al. · Joint Research Centre (European Commission) · 2004 · 203 citations

Agriculture, Animal Sciences, Animal Welfare +9

‘Stoffenmanager’, a Web-Based Control Banding Tool Using an Exposure Process Model

Hans Marquart, Henri Heussen, Maaike le Feber et al. · The Annals of Occupational Hygiene · 2008 · 159 citations · Full text

Pharmacy, Risk Management, Risk Analysis +16