Associations between CYP2E1 promoter polymorphisms and plasma 1,3-dimethyluric acid/theophylline ratios

Genetic Polymorphisms in the 5′-Flanking Region Change Transcriptional Regulation of the Human Cytochrome P450IIE1 Gene1

Shin‐ichi Hayashi, Junko Watanabe, Kaname Kawajiri · The Journal of Biochemistry · 1991 · 677 citations

Life Sciences, Genetics, Molecular Genetics +14

Cytochrome P450 2E1 Genotype and the Susceptibility to Antituberculosis Drug–Induced Hepatitis

Yi‐Shin Huang, Herng‐Der Chern, Wei‐Juin Su et al. · Hepatology · 2003 · 427 citations · Full text

Medicine, Pharmacology, Toxicology +15

Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1

Lie Gu, Frank J. Gonzalez, W. Kalow et al. · Pharmacogenetics · 1992 · 326 citations

Medicine, Biochemistry, Pharmacology +17

The detection of linkage disequilibrium between closely linked markers: RFLPs at the AI-CIII apolipoprotein genes.

E. A. Thompson, S S Deeb, David W. Walker et al. · PubMed · 1988 · 247 citations

Life Sciences, Genetics, Molecular Genetics +12

Different Regulation and Expression of the Human CYP2E1 Gene Due to the Rsal Polymorphism in the 5'-Flanking Region1

Junko Watanabe, Shin‐ichi Hayashi, Kaname Kawajiri · The Journal of Biochemistry · 1994 · 214 citations

Medicine, Genetics, Molecular Genetics +13