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Reduction of hERG inhibitory activity in the 4-piperidinyl urea series of H3 antagonists

Michael Berlin, Yoon Joo Lee, Christopher W. Boyce, Yi Wang, Robert Aslanian, Kevin D. McCormick, Steve Sorota, Shirley M. Williams, Robert E. West, Walter A. Korfmacher

Bioorganic & Medicinal Chemistry Letters · 2010 · 12 citations · 6 references

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6

Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor

Jean‐Michel Arrang, M. Garbarg, Jean‐Charles Schwartz · Nature · 1983 · 1.6K citations

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Optimisation and validation of a medium-throughput electrophysiology-based hERG assay using IonWorks™ HT

Matt Bridgland-Taylor, Alee Hargreaves, Alison Easter et al. · Journal of Pharmacological and Toxicological Methods · 2006 · 150 citations

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Combined Histamine H <sub>1</sub> and H <sub>3</sub> Receptor Blockade Produces Nasal Decongestion in an Experimental Model of Nasal Congestion

Robbie L. McLeod, Garfield G. Mingo, Christine Herczku et al. · American Journal of Rhinology · 1999 · 80 citations

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Characterization of a hERG Screen Using the IonWorks HT: Comparison to a hERG Rubidium Efflux Screen

Steve Sorota, Xue‐Song Zhang, Michael Margulis et al. · Assay and Drug Development Technologies · 2005 · 76 citations

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The Histamine H3 Receptor - A Target for New Drugs

JM Arrang · Pharmacochemistry library · 1998 · 50 citations

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