Concepedia

Efavirenz-mediated induction of omeprazole metabolism is CYP2C19 genotype dependent

Véronique Michaud, Yvonne Kreutz, TC Skaar, Evan T. Ogburn, Nancy Thong, D A Flockhart, Zereunesay Desta

The Pharmacogenomics Journal · 2013 · 21 citations · 41 references

DOI

Concepts

References

41

A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants

Sung Eun Sim, Carl Risinger, Eleni Aklillu et al. · Clinical Pharmacology & Therapeutics · 2006 · 729 citations

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Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study.

David W. Haas, Heather J. Ribaudo, Richard B. Kim et al. · PubMed · 2004 · 629 citations

, , +17

The Cytochrome P450 2B6 (CYP2B6) Is the Main Catalyst of Efavirenz Primary and Secondary Metabolism: Implication for HIV/AIDS Therapy and Utility of Efavirenz as a Substrate Marker of CYP2B6 Catalytic Activity

Bryan A. Ward, J. Christopher Gorski, David R. Jones et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 594 citations

, , +17

St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4

Daniel Dürr · Clinical Pharmacology & Therapeutics · 2000 · 587 citations

, , +15

Cytochrome 2C19*17 Allelic Variant, Platelet Aggregation, Bleeding Events, and Stent Thrombosis in Clopidogrel-Treated Patients With Coronary Stent Placement

Dirk Sibbing, Werner Koch, Daniela Gebhard et al. · Circulation · 2010 · 583 citations

, , +17