Vaccine requirements for sustained cellular immunity to an intracellular parasitic infection

T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

Stephen P. Schoenberger, René E. M. Toes, Ellen I. H. van der Voort et al. · Nature · 1998 · 2.6K citations

Life Sciences, Cell Biology, Immunology +15

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

J P Ridge, Francesca Di Rosa, Polly Matzinger · Nature · 1998 · 2.3K citations

Life Sciences, Cell Biology, Immunology +13

Help for cytotoxic-T-cell responses is mediated by CD40 signalling

Sally R.M. Bennett, Freda Karamalis, Richard A. Flavell et al. · Nature · 1998 · 2.1K citations

Life Sciences, Cell Biology, Immunology +12

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.

Dennis M. Klinman, Ae‐Kyung Yi, Serge L. Beaucage et al. · Proceedings of the National Academy of Sciences · 1996 · 1.5K citations

Life Sciences, Immunology, Microbiology +17

Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization

Yukio Sato, Mark Roman, Helen Tighe et al. · Science · 1996 · 1.1K citations

Life Sciences, Biotechnology, Immunology +17