Concepedia

The bile acid sensor FXR regulates insulin transcription and secretion

Barbara Renga, Andrea Mencarelli, Piero Vavassori, Vincenzo Brancaleone, Stefano Fiorucci

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2010 · 187 citations · 44 references

DOI

Concepts

References

44

Identification of a Nuclear Receptor for Bile Acids

Makoto Makishima, Arthur Y. Okamoto, Joyce J. Repa et al. · Science · 1999 · 2.7K citations

, , +17

Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

Derek J. Parks, Steven G. Blanchard, Randy K. Bledsoe et al. · Science · 1999 · 2.2K citations

, , +17

A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis

Bryan Goodwin, Stacey A. Jones, Roger R. Price et al. · Molecular Cell · 2000 · 1.9K citations · Full text

, , +16

Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis

Christopher J. Sinal, Masahiro Tohkin, Masaaki Miyata et al. · Cell · 2000 · 1.8K citations · Full text

, , +12

Identification of a nuclear receptor that is activated by farnesol metabolites

Barry M. Forman, Elizabeth C. Goode, Jasmine Chen et al. · Cell · 1995 · 1.2K citations · Full text

, , +14