Publication | Closed Access
DNA Aptamer‐Mediated Cell Targeting
162
Citations
28
References
2012
Year
ImmunologyImmunoeditingMolecular BiologyImmunotherapeuticsGene DeliveryImmune Cell TherapyImmunotherapyKill Cancer CellsNucleic Acid BiomarkersDna AptamersTumor ImmunityCancer ResearchMolecular OncologyDna ReplicationImmune SurveillanceTumor TargetingCell BiologyCancer ImmunosurveillanceNatural SciencesApt ModificationMedicineGenome Editing
An apt modification: A simple and effective way to modify the cell surface with target-specific ligands, such as DNA aptamers, while minimizing the effects on the modified cells has been developed. After incubating with lipo–aptamer probes, immune cells (red, see scheme) recognize and kill cancer cells (blue) in the cell mixture. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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