Structure of tyrosine phenol-lyase genes from Citrobacter freundii and structural comparison with tryptophanase from Escherichia coli

A simple method for displaying the hydropathic character of a protein

Jack Kyte, Russell F. Doolittle · Journal of Molecular Biology · 1982 · 23.1K citations

Life Sciences, Biochemistry, Molecular Biology +12

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

H.C. Birnboim, Janine Doly · Nucleic Acids Research · 1979 · 14.9K citations · Full text

Life Sciences, Genetics, Molecular Biology +11

Nonchromosomal Antibiotic Resistance in Bacteria: Genetic Transformation of <i>Escherichia coli</i> by R-Factor DNA

Stanley N. Cohen, Annie Chang, Leslie Hsu · Proceedings of the National Academy of Sciences · 1972 · 2.7K citations

Life Sciences, Genetics, Microbiology +15

Preparation of transforming deoxyribonucleic acid by phenol treatment

Hiuga Saito, Kin‐ichiro Miura · Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects · 1963 · 1.8K citations

Pharmacy, Biochemistry, Molecular Biology +10

The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA

W. John Taylor, Johann Ott, Fritz Eckstein · Nucleic Acids Research · 1985 · 848 citations · Full text

Life Sciences, Genetics, Molecular Biology +17