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Potent orally bioavailable purine nucleoside phosphorylase inhibitor BCX-4208 induces apoptosis in B- and T-lymphocytes—A novel treatment approach for autoimmune diseases, organ transplantation and hematologic malignancies

Autoimmune DiseaseAllergyApoptosisImmunologyTumor ImmunityCell DeathImmune RegulationImmune SurveillanceAutoimmunityT Cell ImmunityImmunomodulationImmunotherapeuticsBioavailable PurineAutoimmune DiseasesImmunotherapyMedicineCell Transplantation