Concepedia

Potent orally bioavailable purine nucleoside phosphorylase inhibitor BCX-4208 induces apoptosis in B- and T-lymphocytes—A novel treatment approach for autoimmune diseases, organ transplantation and hematologic malignancies

Shanta Bantia, Cynthia Parker, Ramanda Upshaw, Amanda Cunningham, Pravin L. Kotian, J. Michael Kilpatrick, Phillip Morris, Pooran Chand, Y.S. Babu

International Immunopharmacology · 2010 · 36 citations · 21 references

DOI

Concepts

References

21

NUCLEOSIDE-PHOSPHORYLASE DEFICIENCY IN A CHILD WITH SEVERELY DEFECTIVE T-CELL IMMUNITY AND NORMAL B-CELL IMMUNITY

E.R. Giblett, ArthurJ. Ammann, Robert P. Sandman et al. · The Lancet · 1975 · 863 citations

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Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell–derived factor-1

Jan A. Burger, Nobuhiro Tsukada, Meike Burger et al. · Blood · 2000 · 734 citations · Full text

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Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: Possible role of nucleoside kinase(s)

Dennis A. Carson, Jonathan Kaye, J. Edwin Seegmiller · Proceedings of the National Academy of Sciences · 1977 · 414 citations · Full text

, , +14

Purine Nucleoside Phosphorylase Deficiency

M. Louise Markert · SpringerReference · 2012 · 245 citations

, , +13

Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers

Paula Sherman, James A. Fyfe · Analytical Biochemistry · 1989 · 217 citations

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