Jonathan Kaye

TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion

Omar Khan, Josephine R. Giles, Sierra McDonald et al. · Nature · 2019 · 1.5K citations

Transcriptional Regulation, T-regulatory Cell, Gene Expression +3

TOX is a critical regulator of tumour-specific T cell differentiation

Andrew Scott, Friederike Dündar, Paul Zumbo et al. · Nature · 2019 · 1K citations · Full text

Cancer Immunosurveillance, Lymphocyte Development, T-regulatory Cell +9

Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells.

Jonathan Kaye, S Porcelli, J P Tite et al. · The Journal of Experimental Medicine · 1983 · 648 citations · Full text

Laboratory Immunology, Adaptive Immune System, T-regulatory Cell +18

Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

Jonathan Kaye, Mei-Ling Hsu, Marie-Elizabeth Sauron et al. · Nature · 1989 · 638 citations

Autoimmune Disease, Lymphocyte Development, T-regulatory Cell +10

Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2.

Jonathan Kaye, Steven Gillis, S B Mizel et al. · The Journal of Immunology · 1984 · 521 citations