Concepedia

Amine substituted N-(1H-benzimidazol-2ylmethyl)-5,6,7,8-tetrahydro-8-quinolinamines as CXCR4 antagonists with potent activity against HIV-1

Kristjan S. Gudmundsson, Paul R. Sebahar, Leah D’Aurora Richardson, John F. Miller, Elizabeth M. Turner, John G. Catalano, Andrew Spaltenstein, Wendell Lawrence, Michael M. Thomson, Stephen P. Jenkinson

Bioorganic & Medicinal Chemistry Letters · 2009 · 54 citations · 14 references

DOI

Concepts

References

14

Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population

Hanneke Schuitemaker, M. Koot, Neeltje A. Kootstra et al. · Journal of Virology · 1992 · 1K citations · Full text

, , +16

The Chemokine Receptor CXCR4 Is Required for the Retention of B Lineage and Granulocytic Precursors within the Bone Marrow Microenvironment

Qing Ma, Dan Jones, Timothy A. Springer · Immunity · 1999 · 677 citations · Full text

, , +17

Pharmacokinetics and Safety of AMD-3100, a Novel Antagonist of the CXCR-4 Chemokine Receptor, in Human Volunteers

Craig W. Hendrix, Charles Flexner, R. T. MacFarland et al. · Antimicrobial Agents and Chemotherapy · 2000 · 504 citations

, , +15

A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains

Joanne F. Berson, Deborah Long, Benjamin J. Doranz et al. · Journal of Virology · 1996 · 345 citations · Full text

, , +15

Persistent Induction of the Chemokine Receptor CXCR4 by TGF-β1 on Synovial T Cells Contributes to Their Accumulation Within the Rheumatoid Synovium

Christopher D. Buckley, Nicole Amft, Paul F. Bradfield et al. · The Journal of Immunology · 2000 · 334 citations · Full text

, , +17