Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

Activating Mutations of <i>NOTCH1</i> in Human T Cell Acute Lymphoblastic Leukemia

Andrew P. Weng, Adolfo A. Ferrando, Woojoong Lee et al. · Science · 2004 · 2.7K citations

Hematological Malignancy, Human T-all, Activated Notch1 +13

Risk Alleles for Multiple Sclerosis Identified by a Genomewide Study

New England Journal of Medicine · 2007 · 1.7K citations

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice.

Jacques J. Peschon, Philip Morrissey, Kenneth H. Grabstein et al. · The Journal of Experimental Medicine · 1994 · 1.6K citations · Full text

High Affinity Receptor, Lymphocyte Development, T-regulatory Cell +19

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

Ursula von Freeden-Jeffry, Paulo Vieira, Linda Lucian et al. · The Journal of Experimental Medicine · 1995 · 1.4K citations · Full text

Lymphocyte Development, T-regulatory Cell, Immunology +19

Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

Adolfo A. Ferrando, Donna Neuberg, Jane Staunton et al. · Cancer Cell · 2002 · 1.1K citations · Full text

Hematological Malignancy, Novel Oncogenic Pathways, Mixed-phenotype Acute Leukemia +10