André Bortolini Silveira

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

Priscila Pini Zenatti, Daniel Ribeiro, Wenqing Li et al. · Nature Genetics · 2011 · 413 citations · Full text

Hematological Malignancy, Mixed-phenotype Acute Leukemia, Immunology +5

Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression

Jon D. Larson, Lawryn H. Kasper, Barbara S. Paugh et al. · Cancer Cell · 2018 · 308 citations

Chromatin, Neuro-oncology, Molecular Neuroscience +11

H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo

André Bortolini Silveira, Lawryn H. Kasper, Yiping Fan et al. · Acta Neuropathologica · 2019 · 120 citations · Full text

Neuro-oncology, Glioma, Cell Proliferation +8

Regulation of PTEN by CK2 and Notch1 in primary T-cell acute lymphoblastic leukemia: rationale for combined use of CK2- and  -secretase inhibitors

A. Silva, Patrícia Yoshioka Jotta, André Bortolini Silveira et al. · Haematologica · 2009 · 75 citations · Full text

Hematological Malignancy, Pten Mrna Expression, Signal Transduction +14

N-(1′-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: Synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia

Lívia B. Salum, Alessandra Mascarello, Rafael Renatino Canevarolo et al. · European Journal of Medicinal Chemistry · 2015 · 40 citations · Full text

Medicinal Chemistry, Medicine, Acute Lymphoblastic Leukemia +7