mRNA expression levels of methotrexate resistance-related proteins in childhood leukemia as determined by a standardized competitive template-based RT-PCR method

Analysis of cytokine mRNA and DNA: detection and quantitation by competitive polymerase chain reaction.

Gary Gilliland, Sean Perrin, K L Blanchard et al. · Proceedings of the National Academy of Sciences · 1990 · 1.5K citations

Life Sciences, Immunology, Molecular Biology +8

Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors.

P. G. Johnston, Heinz-Josef Lenz, Cynthia G. Leichman et al. · PubMed · 1995 · 678 citations

Medicine, Molecular Biology, Oncology +17

Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin.

Cynthia G. Leichman, Heinz-Josef Lenz, Lawrence Leichman et al. · Journal of Clinical Oncology · 1997 · 481 citations

Medicine, Oncology, Pharmacology +16

The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer.

Patrick G. Johnston, Edwin R. Fisher, Howard E. Rockette et al. · Journal of Clinical Oncology · 1994 · 409 citations

Medicine, Oncology, Pathology +11

A rapid and versatile method to synthesize internal standards for competitive PCR

Francesco S. Celi, Michael E. Zenilman, Alan R. Shuldiner · Nucleic Acids Research · 1993 · 315 citations

Medicine, Molecular Biology, Molecular Genetics +10