Interleukin-2 is one of the targets of 1,25-dihydroxyvitamin D3 in the immune system

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

Benjamin Sadlack, Hartmut Merz, Hubert Schorle et al. · Cell · 1993 · 1.7K citations

Veterinary Medicine, Immunology, Pathology +14

1α,25-Dihydroxyvitamin D3 Has a Direct Effect on Naive CD4+ T Cells to Enhance the Development of Th2 Cells

André Boonstra, Franck J. Barrat, Chad Crain et al. · The Journal of Immunology · 2001 · 1.1K citations · Full text

Life Sciences, Immunology, Autoimmunity +13

1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis.

Margherita T. Cantorna, Colleen E. Hayes, Hector F. DeLuca · Proceedings of the National Academy of Sciences · 1996 · 718 citations

Life Sciences, Neurology, Neuroscience +17

Expression of 1,25-Dihydroxyvitamin D3 Receptor in the Immune System

Christian Veldman, Margherita T. Cantorna, Hector F. DeLuca · Archives of Biochemistry and Biophysics · 2000 · 707 citations

Life Sciences, Immunology, Immunoregulation +13

1,25-Dihydroxyvitamin D ₃ : a Novel Immunoregulatory Hormone

Constantine D. Tsoukas, Diego M. Provvedini, Stavros C. Manolagas · Science · 1984 · 531 citations

Life Sciences, Endocrinology, Immunology +11