Concepedia

GSK3 inhibitors show benefits in an Alzheimer's disease (AD) model of neurodegeneration but adverse effects in control animals

Shuxin Hu, Aynun N. Begum, Mychica Jones, Mike S. Oh, Walter Beech, Beverly Hudspeth Beech, Fusheng Yang, Pingping Chen, Oliver J. Ubeda, Peter C. Kim,

Neurobiology of Disease · 2008 · 172 citations · 72 references

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72

Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis

Rakez Kayed, Elizabeth Head, Jennifer L. Thompson et al. · Science · 2003 · 4.1K citations

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Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo

Fusheng Yang, Giselle P. Lim, Aynun N. Begum et al. · Journal of Biological Chemistry · 2004 · 2.3K citations · Full text

, , +17

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

Noboru Sato, Laurent Meijer, Léandros Skaltsounis et al. · Nature Medicine · 2003 · 2.1K citations

, , +14

Binding of GSK3β to the APC-β-Catenin Complex and Regulation of Complex Assembly

Bonnee Rubinfeld, Iris Albert, Emilio Porfiri et al. · Science · 1996 · 1.4K citations

, , +17

Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation

Klaus P. Hoeflich, Juan Luo, Elizabeth A. Rubie et al. · Nature · 2000 · 1.4K citations

, , +13