Effect of CYP3A5 Genotype on Renal Allograft Recipients Treated With Tacrolimus

The Banff 97 working classification of renal allograft pathology

Lorraine C. Racusen, Kim Solez, Robert B. Colvin et al. · Kidney International · 1999 · 3.1K citations

Medicine, Nephrology, Pathology +17

The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients

Vincent Haufroid, Michel Mourad, Val rie Van Kerckhove et al. · Pharmacogenetics · 2004 · 445 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat.

Martin Sattler, F. Peter Guengerich, Chul‐Ho Yun et al. · Drug Metabolism and Disposition · 1992 · 389 citations

Medicine, Biochemistry, Pharmacology +17

Impact of cytochrome P450 3A5 genetic polymorphism on tacrolimus doses and concentration-to-dose ratio in renal transplant recipients1 2

Éric Thervet, Dany Anglicheau, Barry P. King et al. · Transplantation · 2003 · 300 citations

Medicine, Pharmacokinetics, Pharmacology +17

Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability.

Alfonso Lampen, Uwe Christians, F. Peter Guengerich et al. · Drug Metabolism and Disposition · 1995 · 273 citations

Medicine, Pharmacokinetics, Pharmacology +17