Combined Glutathione <i>S</i> -transferase T1 and M1 Positive Genotypes Afford Protection Against Type 2 Diabetes in Japanese

Abstract

This study demonstrated that the GSTT1- and GSTT1-/GSTM1- genotypes are independent risk factors for development of Type 2 diabetes regardless of the smoking status of the patient, and that these genotypes and current smoking were interactively associated with the incidence of Type 2 diabetes.