Concepedia

Binding of 5-fluorodeoxyuridylate to thymidylate synthase in human colon adenocarcinoma xenografts

Janet A. Houghton, Pamela M. Torrance, Saeed Radparvar, Larry G. Williams, Peter J. Houghton

European Journal of Cancer and Clinical Oncology · 1986 · 21 citations · 15 references

DOI

Concepts

References

15

Enzyme inhibitors as substrates

R. D. O’Brien · Pesticide Biochemistry and Physiology · 1974 · 347 citations

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Fluorinated Pyrimidines and Their Nucleosides

Charles Heidelberger · 1975 · 338 citations

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Enhanced inhibition of thymidylate synthase by methotrexate polyglutamates.

Carmen J. Allegra, Bruce A. Chabner, J C Drake et al. · Journal of Biological Chemistry · 1985 · 333 citations · Full text

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Biochemical determinants of responsiveness to 5-fluorouracil and its derivatives in xenografts of human colorectal adenocarcinomas in mice.

Janet A. Houghton, Stephen J. Maroda, John O. Phillips et al. · PubMed · 1981 · 194 citations

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Effect of 5,10-methylenetetrahydrofolate on the dissociation of 5-fluoro-2'-deoxyuridylate from thymidylate synthetase: evidence for an ordered mechanism

Peter V. Danenberg, Kathleen D. Danenberg · Biochemistry · 1978 · 173 citations

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