Janet A. Houghton

Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl–mediated drug resistance

Jennifer S. Carew, Steffan T. Nawrocki, Charissa N. Kahue et al. · Blood · 2007 · 484 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Efficacy of topoisomerase I inhibitors, topotecan and irinotecan, administered at low dose levels in protracted schedules to mice bearing xenografts of human tumors

Peter J. Houghton, Pamela J. Cheshire, James D. Hallman et al. · Cancer Chemotherapy and Pharmacology · 1995 · 407 citations

Medicine, Oncology, Pharmacology +12

Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary.

Richard Görlick, Peter M. Anderson, Irene L. Andrulis et al. · PubMed · 2003 · 198 citations

Medicine, Oncology, Pediatrics +16

Biochemical determinants of responsiveness to 5-fluorouracil and its derivatives in xenografts of human colorectal adenocarcinomas in mice.

Janet A. Houghton, Stephen J. Maroda, John O. Phillips et al. · PubMed · 1981 · 194 citations

Medicine, Biochemistry, Oncology +13

Hedgehog Signaling Drives Cellular Survival in Human Colon Carcinoma Cells

Tapati Mazumdar, Jennifer DeVecchio, Ting Shi et al. · Cancer Research · 2010 · 161 citations · Full text

Medicine, Oncology, Pharmacology +17