J C Drake

The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer.

Patrick G. Johnston, Edwin R. Fisher, Howard E. Rockette et al. · Journal of Clinical Oncology · 1994 · 409 citations

Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase.

Edward Chu, David M. Koeller, John Casey et al. · Proceedings of the National Academy of Sciences · 1991 · 384 citations · Full text

Transcriptional Regulation, Protein Expression, Natural Sciences +14

Neurotoxicity and Elevated Cerebrospinal-Fluid Methotrexate Concentration in Meningeal Leukemia

Werner A. Bleyer, J C Drake, Bruce A. Chabner · New England Journal of Medicine · 1973 · 334 citations

Neurotoxicology, Apparent Antifolate Half-life, Pharmacotherapy +25

Enhanced inhibition of thymidylate synthase by methotrexate polyglutamates.

Carmen J. Allegra, Bruce A. Chabner, J C Drake et al. · Journal of Biological Chemistry · 1985 · 330 citations · Full text

Medicinal Chemistry, Biosynthesis, Biochemistry +15

Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates.

Carmen J. Allegra, J C Drake, Jacques Jolivet et al. · Proceedings of the National Academy of Sciences · 1985 · 312 citations · Full text

Medicinal Chemistry, Mtx Polyglutamates, Pharmaceutical Chemistry +12