J C Drake

The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer.

Patrick G. Johnston, Edwin R. Fisher, Howard E. Rockette et al. · Journal of Clinical Oncology · 1994 · 409 citations

Medicine, Oncology, Pathology +11

Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase.

Edward Chu, David M. Koeller, John Casey et al. · Proceedings of the National Academy of Sciences · 1991 · 385 citations

Life Sciences, Biochemistry, Molecular Biology +11

Neurotoxicity and Elevated Cerebrospinal-Fluid Methotrexate Concentration in Meningeal Leukemia

Werner A. Bleyer, J C Drake, Bruce A. Chabner · New England Journal of Medicine · 1973 · 334 citations

Pharmacy, Neurology, Pharmacology +15

Enhanced inhibition of thymidylate synthase by methotrexate polyglutamates.

Carmen J. Allegra, Bruce A. Chabner, J C Drake et al. · Journal of Biological Chemistry · 1985 · 333 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates.

Carmen J. Allegra, J C Drake, Jacques Jolivet et al. · Proceedings of the National Academy of Sciences · 1985 · 313 citations · Full text

Medicine, Oncology, Pharmacology +7