Synthesis of a highly functionalized rigid template by solid phase azomethine ylide cycloaddition

Combinatorial synthesis — the design of compound libraries and their application to drug discovery

N.K. Terrett, Mark Gardner, David W. Gordon et al. · Tetrahedron · 1995 · 657 citations

Pharmacy, Chemistry, Medicinal Chemistry +16

Combinatorial Organic Synthesis of Highly Functionalized Pyrrolidines: Identification of a Potent Angiotensin Converting Enzyme Inhibitor from a Mercaptoacyl Proline Library

Martin M. Murphy, John R. Schullek, Eric M. Gordon et al. · Journal of the American Chemical Society · 1995 · 161 citations

Pharmacy, Chemistry, Medicinal Chemistry +10

Solid-phase synthesis of proline analogs via a three component 1,3-dipolar cycloaddition

Bruce C. Hamper, Daniel R. Dukesherer, Michael S. South · Tetrahedron Letters · 1996 · 87 citations

Pharmacy, Chemistry, Medicinal Chemistry +13

Synthesis of an array of amides by aluminium chloride assisted cleavage of resin-bound esters

David R. Barn, J. Richard Morphy, David C. Rees · Tetrahedron Letters · 1996 · 73 citations

Natural Sciences, Chemical Engineering, Chemistry +10

The mechanism of the racemisation of α-amino acids in the presence of aldehydes

Ronald Grigg, H. Q. Nimal Gunaratne · Tetrahedron Letters · 1983 · 44 citations

Natural Sciences, Biochemistry, Chemistry +5