Combinatorial synthesis — the design of compound libraries and their application to drug discovery

N.K. Terrett, Mark Gardner, David W. Gordon, +2

Tetrahedron

Combinatorial ChemistryDrug DesignMedicineRational Drug DesignCombinatorial Synthesis +5

Toward the semiquantitative estimation of binding constants. Guides for peptide-peptide binding in aqueous solution

Dudley H. Williams, J. P. Cox, Andrew J. Doig, +7

Journal of the American Chemical Society

BiochemistryAqueous SolutionMedicinePeptide LibraryMass Spectrometry +9

<scp><i>S</i></scp><i>taphylococcus aureus</i> haem biosynthesis: characterisation of the enzymes involved in final steps of the pathway

Susana A. L. Lobo, Alan Scott, Marco A.M. Videira, +8

Molecular Microbiology

Self-assembly of zinc aminoporphyrins

Mark Gardner, Andrea J. Guerin, Christopher A. Hunter, +2

New Journal of Chemistry

Inorganic ChemistrySupramolecular AssemblyZinc AminoporphyrinsNmr SpectroscopyEngineering +10

Novel Amino-pyrazole Ureas with Potent In Vitro and In Vivo Antileishmanial Activity

Charles E. Mowbray, Stéphanie Braillard, William C. Speed, +12

Journal of Medicinal Chemistry

Medicinal ChemistryVivo Antileishmanial ActivityBioorganic ChemistryPharmaceutical ChemistryBiochemistry +13

Origins of stereoselectivity in chiral boron enolate aldol reactions: A computational study using transition state modellings

Anna Bernardi, Anna Maria Capelli, Angiolina Comotti, +4

Tetrahedron

Computational StudyEnantioselective SynthesisEngineeringNovel OrganocatalystsTransition State Modellings +8

Studies in marine cembranolide synthesis: A synthesis of 2,3,5-trisubstituted furan intermediates for lophotoxin and pukalide

Ian Paterson, Mark Gardner, B. J. BANKS

Tetrahedron

Marine Cembranolide SynthesisBioorganic ChemistryEngineeringBiochemistry2,3,5-Trisubstituted Furan Intermediates +7

The combinatorial synthesis of a 30,752-compound library: discovery of SAR around the endothelin antagonist, FR-139,317

N.K. Terrett, Dejan Bojanic, David Brown, +5

Bioorganic & Medicinal Chemistry Letters

Combinatorial ChemistryMedicinal ChemistryBiochemistryEndothelin AntagonistNatural Sciences +8

High Throughput Screening Identifies Novel Lead Compounds with Activity against Larval, Juvenile and Adult Schistosoma mansoni

Nuha R. Mansour, Ross A. Paveley, Mark Gardner, +3

PLoS neglected tropical diseases

Lead CompoundsAntiparasitic AgentMalariaHigh ThroughputLead Identification +19

MAIP: a web service for predicting blood‐stage malaria inhibitors

Nicolas Bosc, Eloy Félix, Ricardo Arcila, +13

Journal of Cheminformatics