David C. Rees

World distribution of factor V Leiden

David C. Rees, Michael J. Cox, J. B. Clegg · The Lancet · 1995 · 1.2K citations

Epidemiology, World Distribution

Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria

Manisha Balwani, Eliane Sardh, Paolo Ventura et al. · New England Journal of Medicine · 2020 · 562 citations · Full text

Global distribution of the CCR5 gene 32-basepair deletion

Jeremy Martinson, Nicola H. Chapman, David C. Rees et al. · Nature Genetics · 1997 · 547 citations

Natural Sciences, Genetics, Global Distribution +8

Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor

Timothy Perera, Eleonora Jovcheva, Laurence Mévellec et al. · Molecular Cancer Therapeutics · 2017 · 335 citations · Full text

Fragment-Based Discovery of the Pyrazol-4-yl Urea (AT9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity

Steven Howard, Valério Berdini, John A. Boulstridge et al. · Journal of Medicinal Chemistry · 2008 · 329 citations · Full text

Drug Target, Pyrazol-4-yl Urea, Clinical Candidate +18