Line-field parallel swept source MHz OCT for structural and functional retinal imaging

Daniel Fechtig, Branislav Grajciar, Tilman Schmoll, Cédric Blatter, René M. Werkmeister, Wolfgang Drexler, Rainer A. Leitgeb

Biomedical Optics Express · 2015 · 85 citations · 42 references

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Abstract

We demonstrate three-dimensional structural and functional retinal imaging with line-field parallel swept source imaging (LPSI) at acquisition speeds of up to 1 MHz equivalent A-scan rate with sensitivity better than 93.5 dB at a central wavelength of 840 nm. The results demonstrate competitive sensitivity, speed, image contrast and penetration depth when compared to conventional point scanning OCT. LPSI allows high-speed retinal imaging of function and morphology with commercially available components. We further demonstrate a method that mitigates the effect of the lateral Gaussian intensity distribution across the line focus and demonstrate and discuss the feasibility of high-speed optical angiography for visualization of the retinal microcirculation.

References

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