Diamine-based human histamine H3 receptor antagonists: (4-Aminobutyn-1-yl)benzylamines

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry · 2002 · 8.1K citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor

Jean‐Michel Arrang, M. Garbarg, Jean‐Charles Schwartz · Nature · 1983 · 1.6K citations

Life Sciences, Neuroscience, Pharmacology +14

Reductive Amination of Aldehydes and Ketones with Sodium Triacetoxyborohydride. Studies on Direct and Indirect Reductive Amination Procedures¹

Ahmed F. Abdel‐Magid, Kenneth G. Carson, Bruce D. Harris et al. · The Journal of Organic Chemistry · 1996 · 1.5K citations

Natural Sciences, Chemistry, Catalysis +10

Cloning and Functional Expression of the Human Histamine H₃Receptor

Timothy W. Lovenberg, Barbara Roland, Sandy J. Wilson et al. · Molecular Pharmacology · 1999 · 700 citations · Full text

Life Sciences, Neuroscience, Pharmacology +16