Prolyl oligopeptidase stimulates the aggregation of α-synuclein

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

Life Sciences, Microbiology, Molecular Biology +14

Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease

Mihael H. Polymeropoulos, Christian Lavedan, Elisabeth Leroy et al. · Science · 1997 · 8.2K citations

Life Sciences, Genetics, Molecular Genetics +17

α-Synuclein Locus Triplication Causes Parkinson's Disease

Andrew Singleton, Matthew J. Farrer, Janel Johnson et al. · Science · 2003 · 4.4K citations

Life Sciences, Genetics, Neuroscience +15

α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies

Maria Grazia Spillantini, R. Anthony Crowther, Ross Jakes et al. · Proceedings of the National Academy of Sciences · 1998 · 3.2K citations

Life Sciences, Neurobiology, Neuroscience +17

The new mutation, E46K, of α‐synuclein causes parkinson and Lewy body dementia

J.J. Zarranz, Juan Carlos Gómez‐Esteban, Elena Lezcano et al. · Annals of Neurology · 2003 · 2.7K citations

Life Sciences, Genetics, Neurology +17