Concepedia

Enzyme enhancement activity of N-octyl-β-valienamine on β-glucosidase mutants associated with Gaucher disease

Ke Lei, Haruaki Ninomiya, Michitaka Suzuki, Takehiko Inoue, Miwa Sawa, Masami Iida, Hiroyuki Ida, Yoshikatsu Eto, Seiichiro Ogawa, Kousaku Ohno,

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2007 · 43 citations · 19 references

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19

The metabolic and molecular bases of inherited disease

Ying-Tsong Chen · Medical Entomology and Zoology · 2001 · 6.9K citations

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Replacement Therapy for Inherited Enzyme Deficiency — Macrophage-Targeted Glucocerebrosidase for Gaucher's Disease

Norman W. Barton, Roscoe O. Brady, James M. Dambrosia et al. · New England Journal of Medicine · 1991 · 1.3K citations · Full text

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Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis

Timothy M. Cox, Robin Lachmann, C. E. Hollak et al. · The Lancet · 2000 · 744 citations

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Accelerated transport and maturation of lysosomal α–galactosidase A in Fabry lymphoblasts by an enzyme inhibitor

Jianqiang Fan, Naoki Asano, Yoshiyuki Suzuki · Nature Medicine · 1999 · 613 citations

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Chemical chaperones increase the cellular activity of N370S β-glucosidase: A therapeutic strategy for Gaucher disease

Anu R. Sawkar, Wei‐Chieh Cheng, Ernest Beutler et al. · Proceedings of the National Academy of Sciences · 2002 · 503 citations · Full text

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