Contact Dermatitis · 1996 · 116 citations · 8 references
PharmacyPharmaceutical AnalysisAnalytical ToxicologyForensic Pharmaceutical AnalysisPharmaceutical FormulationAroma CompoundsIngredient AuthenticationBioactive ConstituentsSource Substances
In the present study, we have investigated 42 cosmetic products based on natural ingredients for content of 11 fragrance substances: geraniol, hydroxycitronellal, eugenol, isoeugenol, cinnamic aldehyde, cinnamic alcohol, alpha-amylcinnamic aldehyde, citral, coumarin, dihydrocoumarin and alpha-hexylcinnamic aldehyde. The study revealed that the 91% (20/22) of the natural ingredients based perfumes contained 0.027%-7.706% of 1 to 7 of the target fragrances. Between 1 and 5 of the chemically defined synthetic constituents of fragrance mix were found in 82% (18/22) of the perfumes. 35% (7/20) of the other cosmetic products (shampoos, creams, tonics, etc) were found to contain 0.0003-0.0820% of 1 to 3 of the target fragrances. Relatively high concentrations of hydroxycitronellal, coumarin, cinnamic alcohol and alpha-amyl cinnamic aldehyde were found in some of the investigated products. The detection of hydroxycitronellal and alpha-hexylcinnamic aldehyde in some of the products demonstrates that artificial fragrances, i.e., compounds not yet regarded as natural substances, may be present in products claimed to be based on natural ingredients.
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Perfumes: art, science and technology
Choice Reviews Online · 1992 · 218 citations
Humanities, Art History, Design +5
Contact allergy to cosmetics: causative ingredients
Anton C. de Groot · Contact Dermatitis · 1987 · 150 citations
Life Sciences, Dermatology, Allergy +16