A 13-bp deletion in αIIb gene is a founder mutation that predominates in Palestinian-Arab patients with Glanzmann thrombasthenia

The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: Causes and consequences

Michael Krawczak, Jochen Reiss, D.N. Cooper · Human Genetics · 1992 · 1.4K citations

Life Sciences, Genetics, Molecular Genetics +17

Crystal Structure of the Extracellular Segment of Integrin αVβ3

Jian-Ping Xiong, Thilo Stehle, Beate Diefenbach et al. · Science · 2001 · 1.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics

Tsan Sam Xiao, Junichi Takagi, Barry S. Coller et al. · Nature · 2004 · 842 citations

Life Sciences, Biochemistry, Molecular Biology +14

Genetic analysis of idiopathic torsion dystonia in Ashkenazi Jews and their recent descent from a small founder population

Neil Risch, Deborah de Leon, Laurie J. Ozelius et al. · Nature Genetics · 1995 · 431 citations

Life Sciences, Genetics, Neurology +13

Ser-752-->Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann thrombasthenia.

Y P Chen, Isabelle Djaffar, Dominique Pidard et al. · Proceedings of the National Academy of Sciences · 1992 · 230 citations · Full text

Medicine, Biochemistry, Molecular Biology +17