Oncogene · 2009 · 16 citations · 23 references
MedicineCancer BiologyMolecular BiologyMolecular OncologyTranscriptionTranscriptional RegulationCancer Cell SignalingDna Damage-induced ApoptosisTranscription FactorsTranscription In EukaryotesTumor Suppressor Gene InactivationTumor Suppressor GenesP53 InactivationP53-mediated ApoptosisTumor Suppression MechanismsTumor Suppression PathwaysTumor Suppressor P53
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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
Lawrence A. Donehower, Michele Harvey, Betty L. Slagle et al. · Nature · 1992 · 4.7K citations
Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
Pumin Zhang, J. Wade Harper, Stephen J. Elledge et al. · Cell · 1995 · 2.1K citations · Full text
Tumor spectrum analysis in p53-mutant mice
Tyler Jacks, Lee Ann Remington, Bart O. Williams et al. · Current Biology · 1994 · 2.1K citations
Medicine, Cancer Biology, Oncology +12
Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome
Kenneth P. Olive, David A. Tuveson, Zachary C. Ruhe et al. · Cell · 2004 · 1.3K citations · Full text