Concepedia

SAR profiles of spirocyclic nicotinamide derived selective HDAC1/HDAC2 inhibitors (SHI-1:2)

Joey L. Methot, Christopher L. Hamblett, Dawn M. Mampreian, Joon Jung, Andreas Harsch, Alexander A. Szewczak, William K. Dahlberg, Richard E. Middleton, Bethany Hughes, Judith C. Fleming,

Bioorganic & Medicinal Chemistry Letters · 2008 · 44 citations · 22 references

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References

22

Three proteins define a class of human histone deacetylases related to yeast Hda1p

Christina M. Grozinger, Christian A. Hassig, Stuart L. Schreiber · Proceedings of the National Academy of Sciences · 1999 · 762 citations

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Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression

G. Lagger, Dónal O’Carroll, Martina Rembold et al. · The EMBO Journal · 2002 · 757 citations · Full text

, , +13

Histone Deacetylase 3 (HDAC3) and Other Class I HDACs Regulate Colon Cell Maturation and p21 Expression and Are Deregulated in Human Colon Cancer

Andrew J. Wilson, Do-Sun Byun, Lucas B. Murray et al. · Journal of Biological Chemistry · 2006 · 581 citations · Full text

, , +17

New insights about HERG blockade obtained from protein modeling, potential energy mapping, and docking studies

Ramy Farid, Tyler Day, Richard A. Friesner et al. · Bioorganic & Medicinal Chemistry · 2006 · 504 citations

, , +17

Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy

Wilko Weichert, A.-E. Roske, Volker Gekeler et al. · British Journal of Cancer · 2008 · 479 citations · Full text

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