Bethany Hughes

Statistics

Publications

Citations

651

H-Index

Active since

2007

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

United States Military Academy

Bethany Hughes is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in enzyme inhibition, pharmacology, and medicinal chemistry.

Publications per year

2007–2015

Publications

Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)

Joey L. Methot, Prasun K. Chakravarty, Mélissa Chénard et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 187 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +10

PI3K Signaling Through the Dual GTPase–Activating Protein ARAP3 Is Essential for Developmental Angiogenesis

Laure Gambardella, Myriam Hemberger, Bethany Hughes et al. · Science Signaling · 2010 · 50 citations

Life Sciences, Developmental Biology, Molecular Biology +11

SAR profiles of spirocyclic nicotinamide derived selective HDAC1/HDAC2 inhibitors (SHI-1:2)

Joey L. Methot, Christopher L. Hamblett, Dawn M. Mampreian et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 44 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

The discovery of 6-amino nicotinamides as potent and selective histone deacetylase inhibitors

Christopher L. Hamblett, Joey L. Methot, Dawn M. Mampreian et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 43 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Piperazinyl pyrimidine derivatives as potent γ-secretase modulators

Alexey Rivkin, Sean P. Ahearn, Stephanie M. Chichetti et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 41 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +9

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