Concepedia

Zebrafish as a Model Organism for the Identification and Characterization of Drugs and Genes Affecting p53 Signaling

Ulrike Langheinrich, Elisabeth Hennen, Gordon M. Stott, Gabi Vacun

Current Biology · 2002 · 380 citations · 23 references

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23

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Lawrence A. Donehower, Michele Harvey, Betty L. Slagle et al. · Nature · 1992 · 4.7K citations

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Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations

, , +10

Effective targeted gene ‘knockdown’ in zebrafish

Aidas Nasevicius, Stephen C. Ekker · Nature Genetics · 2000 · 2.5K citations

, , +10

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

Roberto Montes de Oca Luna, Daniel S. Wagner, Guillermina Lozano · Nature · 1995 · 1.4K citations

, , +12

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

Stephen N. Jones, Amy E. Roe, Lawrence A. Donehower et al. · Nature · 1995 · 1.3K citations

, , +11