Applied Physics Letters · 2009 · 53 citations · 16 references
Natural SciencesImmunologyMolecular DiagnosticsMolecular PhysicsSpectroscopyMass SpectrometrySingle-molecule DetectionMass Spectrometry-based DetectionResponse TimeUltrasensitive Detection
Superconducting stripline detectors (SSLDs) are promising for detecting keV molecules at nanosecond response times and with mass-independent detection efficiency. However, a fast response time is incompatible with practical centimeter detector size. A parallel configuration of striplines provides a means to address this problem. Experimental results and simulation for promisingly large 1-mm-square parallel niobium SSLDs show that nanosecond pulses are produced by superconducting-normal transition within only one of the parallel striplines instead of cascade switching of all the parallel striplines. Successful detection of a series of multimers of immunoglobulin G up to 584 kDa supports the mass-independent efficiency for mass spectrometry.
16
<i>Introduction to Superconductivity</i>
M. Tinkham, V. J. Emery · Physics Today · 1996 · 6.7K citations