Utility of serum interleukin-6 for diagnosis of invasive bacterial disease in children

Shock and Tissue Injury Induced by Recombinant Human Cachectin

Kevin J. Tracey, Bruce Beutler, Stephen F. Lowry et al. · Science · 1986 · 2.6K citations

Veterinary Medicine, Immunology, Physiology +17

Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.

Jack Gauldie, Carl D. Richards, D.C. Harnish et al. · Proceedings of the National Academy of Sciences · 1987 · 1.7K citations · Full text

Life Sciences, Immunology, Pathology +15

Treatment of Gram-Negative Bacteremia and Septic Shock with HA-1A Human Monoclonal Antibody against Endotoxin

Elizabeth Ziegler, Charles J. Fisher, Charles L. Sprung et al. · New England Journal of Medicine · 1991 · 1.6K citations · Full text

Veterinary Medicine, Immunology, Pharmacotherapy +17

The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome.

Anders Waage, P Brandtzæg, Alfred Halstensen et al. · The Journal of Experimental Medicine · 1989 · 1.2K citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +9

Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition.

Seijiro Okusawa, Jeffrey A. Gelfand, Takashi Ikejima et al. · Journal of Clinical Investigation · 1988 · 988 citations · Full text

Medicine, Immunology, Pharmacology +17