Concepedia

Potentiometric determination of octanol–water and liposome–water partition coefficients (logP) of ionizable organic compounds

Claire Barzanti, Rebecca Evans, Jérémy Fouquet, Léonard Gouzin, Nicola M. Howarth, Gary Kean, Emilie Levet, Daniel Wang, Estelle Wayemberg, Agnes A Yeboah,

Tetrahedron Letters · 2007 · 34 citations · 21 references

DOI

Concepts

References

21

pH-Metric log P. 3. Glass electrode calibration in methanol-water, applied to pKa determination of water-insoluble substances

Alex Avdeef, John Comer, Simon Thomson · Analytical Chemistry · 1993 · 256 citations

, , +16

PH-metric log P 11. p K a determination of water-insoluble drugs in organic solvent–water mixtures

Alex Avdeef, Karl Box, John Comer et al. · Journal of Pharmaceutical and Biomedical Analysis · 1999 · 224 citations

, , +15

Microelectrometric titration measurement of the pKa's and partition and drug distribution coefficients of narcotics and narcotic antagonists and their pH and temperature dependence

Joyce J. Kaufman, Nora Semo, W. S. Koski · Journal of Medicinal Chemistry · 1975 · 212 citations

, , +8

Drug Liposome Partitioning as a Tool for the Prediction of Human Passive Intestinal Absorption

K. Balon, Bernd Riebesehl, Bernhard Müller · Pharmaceutical Research · 1999 · 199 citations

, , +12

pH‐Metric log P. Part 1. Difference Plots for Determining Ion‐Pair Octanol‐Water Partition Coefficients of Multiprotic Substances

Alex Avdeef · Quantitative Structure-Activity Relationships · 1992 · 173 citations

, , +12