Concepedia

Mutagenicity of metabolically activated benzo[a]anthracene 3,4-dihydrodiol: Evidence for bay region activation of carcinogenic polycyclic hydrocarbons

Alexander W. Wood, Wayne Levin, Albert Lu, D. W. Ryan, S.B. West, Roland E. Lehr, Maria Schaefer-Ridder, D. M. JERINA, Allan H. Conney

Biochemical and Biophysical Research Communications · 1976 · 95 citations · 9 references

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References

9

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide

Peter Sims, P.L. Grover, Alan Swaisland et al. · Nature · 1974 · 1.1K citations

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Metabolism of benzo(a)pyrene and benzo (a)pyrene derivatives to mutagenic products by highly purified hepatic microsomal enzymes.

Alexander W. Wood, Wayne Levin, Albert Lu et al. · Journal of Biological Chemistry · 1976 · 313 citations · Full text

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Metabolic conversion of benzo[a]pyrene by Syrian hamster liver microsomes and binding of metabolites to deoxyribonucleic acid

A. Borgen, H. Darvey, Neal Castagnoli et al. · Journal of Medicinal Chemistry · 1973 · 311 citations

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Exceptional mutagenicity of a benzo[a]pyrene diol epoxide in cultured mammalian cells

Robert F. Newbold, P. Brookes · Nature · 1976 · 270 citations

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Mutagenicity and cytotoxicity of benzo(a)pyrene benzo-ring epoxides.

Wood Aw, Wislocki Pg, Chang Rl et al. · PubMed · 1976 · 225 citations

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