Concepedia

WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: Identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers

Che‐Jen Hsiao, Tsai‐Kun Li, Ya‐Ling Chan, Ling‐Wei Hsin, Cho-Hwa Liao, Chien-Hua Lee, Ping‐Chiang Lyu, Jih‐Hwa Guh

Biochemical Pharmacology · 2007 · 42 citations · 21 references

DOI

Concepts

References

21

Arginine-Rich Molecular Transporters for Drug Delivery:  Role of Backbone Spacing in Cellular Uptake

Jonathan B. Rothbard, Erik Kreider, Christopher L. VanDeusen et al. · Journal of Medicinal Chemistry · 2002 · 324 citations

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Doxorubicin encapsulation and diffusional release from stable, polymeric, hydrogel nanoparticles

D. Missirlis, Ryuzo Kawamura, Nicola Tirelli et al. · European Journal of Pharmaceutical Sciences · 2006 · 210 citations

, , +16

1,25-Dihydroxyvitamin D3 enhances the susceptibility of breast cancer cells to doxorubicin-induced oxidative damage.

Amiram Ravid, Dafna Rocker, Arthur Machlenkin et al. · PubMed · 1999 · 161 citations

, , +14

Topoisomerase II and histone deacetylase inhibitors delay the G2/M transition by triggering the p38 MAPK checkpoint pathway

Alexei Mikhailov, Mio Shinohara, Conly L. Rieder · The Journal of Cell Biology · 2004 · 152 citations · Full text

, , +17

Regulation of Ich-1 pre-mRNA alternative splicing and apoptosis by mammalian splicing factors

Zhi‐Hong Jiang, Wanjiang Zhang, Yi Rao et al. · Proceedings of the National Academy of Sciences · 1998 · 143 citations

, , +15