Concepedia

Prediction of hepatic first-pass metabolism and plasma levels following intravenous and oral administration of barbiturates in the rabbit based on quantitative structure—Pharmacokinetic relationships

Nobutoshi Watari, Yuichi Sugiyama, NOBUYOSHI KANENIWA, Mituru Hiura

Journal of Pharmacokinetics and Biopharmaceutics · 1988 · 28 citations · 38 references

DOI

Concepts

References

38

<i>p</i>-σ-π Analysis. A Method for the Correlation of Biological Activity and Chemical Structure

Corwin Hansch, Toshio Fujita · Journal of the American Chemical Society · 1964 · 2.3K citations

, , +8

A physiological approach to hepatic drug clearance

G. Wilkinson, David G. Shand · Clinical Pharmacology & Therapeutics · 1975 · 1.9K citations

, , +17

Statistical moments in pharmacokinetics

Kiyoshi Yamaoka, Terumichi Nakagawa, Toyozo Uno · Journal of Pharmacokinetics and Biopharmaceutics · 1978 · 1.3K citations

, , +5

Quantitative approach to biochemical structure-activity relationships

Corwin Hansch · Accounts of Chemical Research · 1969 · 919 citations

, , +7

Hepatic clearance of drugs. I. Theoretical considerations of a “well-stirred” model and a “parallel tube” model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance

K. Sandy Pang, Malcolm Rowland · Journal of Pharmacokinetics and Biopharmaceutics · 1977 · 798 citations

, , +17