Nature Medicine · 2011 · 218 citations · 53 references
Life SciencesCell BiologyMolecular BiologyCancer GeneticsDna ReplicationMolecular OncologyCell Cycle DeregulationCell-cycle CheckpointsDna Damage-induced Apoptosis53Bp1 RecruitmentP53 InactivationTumor Suppressor P53
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WAF1, a potential mediator of p53 tumor suppression
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In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
Lyubomir T. Vassilev, Binh Thanh Vu, Bradford Graves et al. · Science · 2004 · 4.7K citations
Medicine, Oncology, Pharmacology +15
Mdm2 promotes the rapid degradation of p53
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