Serum Concentrations of Estrogen, Testosterone and Gonadotropins in Osteoporotic and Nonosteoporotic Postmenopausal Women

Abstract

In a group of women with vertebral compression fractures due to postmenopausal osteoporosis, values for plasma testosterone, serum estrogen, and serum gonadotropins were not significantly different from those in an agematched control group. The results do not support the suggestion that women in whom clinically apparent osteoporosis develops postmenopausally have a greater postmenopausal decline in sex hormone production. We conclude that some factor (or factors) in addition to the menopause is present in osteoporotic patients that accelerates bone loss.