Menopause is an academic concept and research domain centered on the natural biological transition in the female reproductive system characterized by the permanent cessation of menstruation. This field investigates the underlying physiological and hormonal changes, associated physical and psychological symptoms, long-term health implications, and the socio-cultural context of this life stage. Key characteristics include its clinical definition by 12 consecutive months of amenorrhea and the multidisciplinary study of its biological basis and its impact on health and well-being.